I don't have an ipod.
But I guess if I had a most played list on my frostwire it'd contain mostly Bloc Party, Smashing Pumpkins, Kings of Leon, Red Hot Chili Peppers, Ian Dury, Manic Street Preachers, Th Strokes and Dire Straits.
I've also recently discovered Elbow - they'll be creeping up my non-exsitent most played list soon.
Elbow:
http://www.youtube.com/watch?v=hk2xaeXnxlM
http://www.youtube.com/watch?v=fX0B9ZpdZEA
http://www.youtube.com/watch?v=-ITMRHJnaJY